The instructions that make us who we are translate into a diverse array of complex and highly regulated processes that occur precisely and on time in every single cell. Mistakes in these processes can lead to disease. Scientists at the Max Perutz Labs study fundamental cellular and developmental processes at a mechanistic level.
Genetic information is encoded in genes, embedded in chromatin, and organized in chromosomes. Its implementation is dynamically regulated at different levels from DNA to RNA. At the Max Perutz Labs, scientists focus on fundamental processes of inheritance, nuclear architecture, genome organization, and RNA biology from bacteria to humans.
Malfunctions in our defense systems account for more than 85% of all human deaths. Max Perutz Labs scientists dissect the molecular mechanisms underlying the regulation of immune tolerance, signaling pathways in sterile and pathogenic inflammation, including cancer, as well as the principal mechanisms of immune surveillance in healthy, autoimmune, and infectious disease settings.
Biological processes are driven by the coordinated interaction of molecules within cells and tissues. The Max Perutz Labs studies how structure is related to function, the dynamics and energetics of the macromolecules that are at the heart of these processes, and the networks in which they operate. We aim to elucidate the mechanisms that shape our normal physiology and rationalize the role of aberrant macromolecules in disease.
Starting in April 2024
Erinc Hallacli
Deciphering molecular phenotypes in neurodegenerative diseases
Chromatin as a gatekeeper of chromosome replication
11:30 - 12:30
Max Perutz Labs SR 1 (6th floor)Mind matters. VBC mental health awareness
13:30 - 14:30 IMP Lecture HallThe multiple facets of Hop1 during meiotic prophase
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Chromosomes as Mechanical Objects: from E.coli to Meiosis to Mammalian cells
11:00 - 12:00 IMBA/GMI Lecture HallConvergent evolution of CO2-fixing liquid-liquid phase separation
11:30 - 12:30 GMI Orange Seminar RoomViral envelope engineering for cell type specific delivery
16:00 - 17:00 IMP Seminar Room 1.014/16New ways of leading: inclusive leadership and revising academic hierarchies
14:15 - 15:15 IMP Lecture HallHow an opportunistic human pathogen colonizes surfaces - From pathogen behavior to new drugs
13:15 - 14:15 UBB - Lecture Hall 1Title to be announced
14:00 - 15:00 Lecture Hall AandB, VBC5Decoding Molecular Plasticity in the Dark Proteome of the Nuclear Pore Complex
11:00 - 12:00 IMBA/GMI Lecture HallProbing the 3D genome architectural basis of neurodevelopment and aging in vivo
17:00 - 18:00 ZoomHow to tango with four - the evolution of meiotic chromosome segregation after genome duplication
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Multidimensional approach to decoding the mysteries of animal development
13:15 - 14:15 UBB - Lecture Hall 1Connecting mitotic chromosomes to dynamic microtubules - insight from biochemical reconstitution
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Membrane remodeling proteins at the junction between prokaryotes and eukaryotes
13:15 - 14:15 UBB - Lecture Hall 1Neurodiversity in academia: strengths and challenges of neurodivergence
14:00 - 15:00 IMP Seminar Room 1.014/16Gene expression dynamics during the awakening of the zygotic genome
11:00 - 12:00 IMBA/GMI Lecture HallWhen all is lost? Measuring historical signals
13:15 - 14:15 UBB - Lecture Hall 1Suckers and segments of the octopus arm
11:00 - 12:00 IMBA/GMI Lecture HallUsing the house mouse radiation to study the rapid evolution of genes and genetic processes
13:15 - 14:15 UBB - Lecture Hall 1CRISPR jumps ahead: mechanistic insights into CRISPR-associated transposons
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Title to be announced
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Enigmatic evolutionary origin and multipotency of the neural crest cells - major drivers of vertebrate evolution
13:15 - 14:15 UBB - Lecture Hall 1Visualising mitotic chromosomes and nuclear dynamics by correlative light and electron microscopy
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Bacterial cell envelope homeostasis at the (post)transcriptional level
13:15 - 14:15 UBB - Lecture Hall 1Polyploidy and rediploidisation in stressful times
13:15 - 14:15 UBB - Lecture Hall 1Prdm9 control of meiotic synapsis of homologs in intersubspecific hybrids
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)RNA virus from museum specimens
13:15 - 14:15 UBB - Lecture Hall 1Programmed DNA double-strand breaks during meiosis: Mechanism and evolution
11:30 - 12:30 Max Perutz Labs SR 1 (6th floor)Title to be announced
11:00 - 12:00
